Assuming that the clinical requirements for a barrier membrane are satisfied, individual preferences for the handling properties play a major role in the choice of collagen membranes. The easy handling of naturesQue ColTect P enables diverse applications in therapeutic concepts that include the use of regenerative measures.

Structure, design, and stability

naturesQue ColTect P is manufactured from purified collagen-rich tissue. Using a gentle method, the collagen is minimally crosslinked to give the membrane a predictable resorption profile with maximum tissue tolerability. A crosslinked structure prevents premature enzymatic cleavage of the collagen fibers and gives naturesQue ColTect P a reproducible and reliable barrier function that is adapted to the time profile of bone healing.

This produces a highly versatile and strong membrane with comfortable handling properties. naturesQue ColTect P is made up of a layer of intact collagen fibers. The membrane is not side specific.

Requirements profile for a collagen membrane

Collagen membranes alone do not have sufficient mechanical stability to shape and protect defect contours. For this reason naturesQue ColTect P is used together with bone substitute materials such as naturesQue SemOss B or naturesQue MaxOss P.

The use of bone substitute materials creates a volumizing framework in the defect space that is used by the osteoblasts as a substrate for bone deposition.

A barrier membrane protects the spaces in the bone defect and prevents the ingrowth of soft tissues. The job of the membrane is to establish and maintain a barrier that is permeable to nutrients between the bone and soft tissue. The membrane also stabilizes the augmentation material by covering the bone defect. The barrier function of naturesQue ColTect P lasts about 3 months, which is sufficiently long to ensure adequate bone healing.

Handling and feel

The naturesQue ColTect P membrane can be applied wet or dry. The membrane is cut to size so that the piece overlaps the margin of the defect by about 2 mm. When dry, naturesQue ColTect P is a sturdy, stable membrane. Wetting the membrane with saline or blood makes naturesQue ColTect P flexible, enabling it to be adapted to the defect contours.

It is not usually necessary to fix naturesQue ColTect P because the membrane can be easily wetted and adheres to the bone walls. Nevertheless, naturesQue ColTect P can be repositioned should this be necessary. If needed, naturesQue ColTect P can be sutured or fixed with pins.

naturesQue ColTect P put into context

Origin

• Porcine peritoneum

Composition

• Intact collagen fibers
• Stabilized by reliable minimal crosslinking

Processing

• Collagen-rich peritoneum
• Cleaning and removal of non-collagenous proteins
• Stabilization of the collagen fibers using minimal crosslinking
• Washing, rinsing, and drying
• Measurement, packaging, and sterilization
• Quality Control

Application

• Remove with sterile instruments
• Processed wet or dry
• Adapt to the size of the defect, overlapping by about 2 mm
• Closed healing is recommended
• No specific side for positioning
• Can be repositioned

Consistency/Feel

• Dry: Stable and rigid, sturdy
• Wet: Can be draped, sturdy, adhesive, not sticky
• Does not stretch
• Tear resistant

Resorption

• Resorption time between 12 and 16 weeks